RADNOR, Pa., March 16, 2022 — (PRNewswire) — The Quest for Sleep, a feature-length documentary about the human toll of insomnia and science of sleep, is released today on Facebook as a world premiere streaming event at 8:00 PM ET/5:00 PM PT, followed by select theatrical screenings in New York City and Los Angeles. Supported by Idorsia Pharmaceuticals U.S., the film follows the lives of real people who struggle with insomnia on their journey to find hope through scientific insights that illuminate the relationship between sleep, insomnia and the brain and body. The character of "Sleep" is narrated by award-winning actor, Octavia Spencer, who acts as an empathetic and discerning foil to the cast and connects the audience to sleep and neuroscience experts. Also featured in the film are professional basketball player, Andre Iguodala, Olympic runner, Emma Coburn and US Army Retired Lieutenant General, Rick Lynch.

Tying together the film's compelling stories and the science of sleep, Octavia Spencer's narration offers a poetic, witty and understanding voice to the struggles and hopes of the people featured in the film. "Sleep" leads the audience through powerful 3D animation that takes viewers inside the brains of the characters as the stories of their lives are playing out.

"As someone who has experienced the impact of trouble sleeping, I immediately felt a connection to the people in the film and their struggles with insomnia," says Octavia Spencer. "Being involved in this documentary has granted me the opportunity to shine a light on a topic that many people often don't feel comfortable discussing with others, and I want them to know they aren't alone. This film brings insomnia to the forefront, and I hope it prompts a robust dialogue about this condition that impacts so many people."

The Quest for Sleep's goal is to encourage people to start talking about and prioritizing their sleep health, while also educating audiences about insomnia's impact on both nights and days. In the United States, insomnia is the most prevalent sleep/wake disorder, affecting approximately 25 million adults nationwide.^1,2,3 Poor quality or insufficient sleep can affect many aspects of the daily lives of people with trouble sleeping including the ability to concentrate, mood and energy levels.³ In the long-term, insomnia is associated with numerous serious health conditions, such as psychiatric disorders, cardiovascular disease, type 2 diabetes, substance abuse and dementia.^4,5,6

Throughout the film, viewers will see the real stories of people whose different perspectives reveal the many facets of the sleep disorder across diverse backgrounds, lifestyles and personalities.

• Andre, Professional Basketball Player: A busy professional athlete, entrepreneur, husband and father who improves his sleep habits with the help of a sleep therapist.
• Emma, Professional Runner & Steeple Chase World Champion: A professional athlete, philanthropist and wife who prioritizes healthy sleep to perform.
• Kelly, The Nurse: A nurse, hesitant to discuss her insomnia, struggles to give herself as much care as she gives her community.
• Lois, The Magazine Editor: A magazine editor, who is ready to reclaim her health, discovers the roots of her anxiety around sleep.
• KK, The Salon Owner: A salon owner tries to leave her maddening insomnia at the shop door, morning after morning.
• Margaret, The Psychotherapist: A psychotherapist wanders her home night after night and finally tries to make sleep her friend.
• Rick, US Army Retired Lieutenant General: A retired U.S. military commander who wants both soldiers and citizens to know it's okay to ask for help.
• Yurica, The Energy Consultant: An energy consultant in Costa Rica tries to get to bed earlier so he can work on his relationship with his wife.
• Steve, The Performer: A singer's sleep deprivation keeps his nightly routine unpredictable.

In addition to the everyday voices, experts in the sleep space, including Dayna Johnson, PhD, MPH, MSW, MS; Sleep Epidemiologist, Michael Grandner, PhD, MTR, Behavioral Sleep Medicine Specialist, and Meeta Singh, MD, Psychiatrist and Sleep Medicine Specialist, share information on the science behind sleep and provide insights into what happens inside the body and brain when there is a lack of sleep.

"Despite the prevalence of insomnia, many people who live with this debilitating condition feel isolated on their journey to find quality sleep and often don't feel comfortable speaking openly about their struggles," says Patricia Torr, President and General Manager of Idorsia U.S., the company which sponsored the film. "Through the compelling stories of those featured in the film, audiences get an inside peek of what it's like to live with insomnia, while also learning about the science of insomnia from experts. It's our hope that that this film will become a powerful, unique resource for both patients and healthcare professionals alike, and inspire people to share their stories and prompt more open conversations."

In addition to the Facebook Live streaming premiere, The Quest for Sleep will make its theatrical debut in select locations in New York and Los Angeles from March 18-20. To learn more about where to watch, please visit TheQuestForSleep.com and follow on Twitter, Facebook, Instagram and YouTube.

Notes to the editor

About The Quest for Sleep

The Quest for Sleep is a feature-length documentary that follows real individuals, whose struggles with sleep threaten to unravel their waking lives. The voice of Sleep itself — narrated by award-winning actor Octavia Spencer — acts as an enigmatic and insightful complement to the cast. She helps lead the audience to experts who illuminate the science behind how we sleep, and what can keep us awake. Through stunning 2D & 3D animation, the documentary delves into the themes of regular wake-sleep patterns, the causes and risks of insomnia and the effects of insomnia on the brain and body. The documentary, in association with Idorsia U.S., was produced by Osmosis Films and is being released by Abramorama.

About Insomnia

Insomnia is defined as a combination of difficulty obtaining sufficient sleep and dissatisfaction with sleep combined with a significant negative impact on daytime functioning. Chronic insomnia is defined as difficulty initiating and/or maintaining sleep on at least three nights per week for at least three months, despite adequate opportunity to sleep.

Insomnia is a condition of overactive brain activity during sleep, and studies have shown that areas of the brain associated with wakefulness remain more active during sleep in patients with insomnia.

Significant insomnia is a common problem with a prevalence of approximately 10%. On this basis, and assuming a U.S. adult population of around 250 million, there are approximately 25 million adults in the U.S. who suffer from insomnia.

Insomnia as a chronic disorder is different from a brief period of poor sleep, and it can take its toll on both physical and mental health. It can be a persistent condition with a negative impact on daytime functioning. Idorsia's research has shown that poor-quality sleep can affect many aspects of daily life, including the ability to concentrate, mood, and energy levels.

The goals of managing insomnia are to improve sleep quality and quantity, as well as daytime functioning. Current recommended treatment of insomnia includes sleep hygiene recommendations, cognitive behavioral therapy, and pharmacotherapy.

About Osmosis Films

Osmosis Films is an award-winning creative studio founded in 2010 which combines global production resources and a unique collaborative process to bring powerful narratives to life across all media types and platforms. Films include the Academy Award short-listed documentary The Lottery and ESPN's 30-for-30 Fernando Nation. Osmosis has created premium documentary content for HBO, ESPN 30 for 30, A&E, A24, Vice and more. For more information, visit www.osmosisfilms.com.

About Abramorama

Abramorama is the preeminent global media distribution and marketing company for nonfiction and music films. An innovator in the focused, personalized form of film distribution, marketing, promotion, and live and event cinema, Abramorama provides customized services to filmmakers, networks, digital services, and IP owners, across all platforms and in all territories. In its over 20 years of operation, Abramorama has been the trusted film partner to many of the most respected global brands in entertainment, including The Beatles, Dolly Parton, Metallica, Pearl Jam, Stevie Nicks, Neil Young, Laurie Anderson, Jimi Hendrix, Green Day, National Geographic, Discovery, AARP, MSNBC, Apple, Amazon, Netflix, HBO, Showtime, Hulu, Universal Music Group, Atlantic Records, Warner Music Group, Sony, Concord Music Group, and many others. Through a powerful global network of cinemas, digital media outlets, and affinity marketing partners, Abramorama strategically implements a unified distribution and audience activation plan for each title. Abramorama is expert at maximizing reach, engagement, marketing spends, and the ROI for content created for target audiences. For more information, visit abramorama.com.

References

1. United States Census Bureau. The U.S. Adult and Under-Age-18 Populations: 2020 Census. 2021 Aug 12.
2. Sateia MJ, Buysse DJ, Krystal AD, Neubauer DN, Heald JL. Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med JCSM. 2017;13(2):307–49.Uhlig B, et al. Sleep Med. 2014;15(6):708-715.
3. Roth T. Insomnia: Definition, prevalence, etiology, and consequences. J. Clin. Sleep Med. 2007;15((Suppl. S5)):S7–S10. doi: 10.5664/jcsm.26929.
4. Olfson M, Wall M, Liu SM, Morin CM, Blanco C. Insomnia and Impaired Quality of Life in the United States. J Clin Psychiatry. 2018 Sep 11;79(5):17m12020. doi: 10.4088/JCP.17m12020. 
5. Doghramji K. The epidemiology and diagnosis of insomnia. Am J Manag Care. 2006 May;12(8 Suppl): S214-20. PMID: 16686591. 
6. de Almondes KM, Costa MV, Malloy-Diniz LF, Diniz BS. Insomnia and risk of dementia in older adults: Systematic review and meta-analysis. J Psychiatr Res. 2016 Jun;77:109-15. doi: 10.1016/j.jpsychires.2016.02.021. Epub 2016 Mar 8. PMID: 27017287. 

About Idorsia U.S.

Idorsia U.S., an affiliate of Idorsia, is reaching out for more – we have more ideas, we see more opportunities, and we want to help more patients. To achieve this, we will help develop Idorsia into a leading biopharmaceutical company, with a strong scientific core. With commercial operations based outside of Philadelphia, PA, one of densest communities of life sciences talent in the world, we are helping to realize the company's ambition of bringing innovative medicines from bench to bedside. Our goal is to build a commercial footprint that will deliver Idorsia's deep pipeline of products from its R&D engine to the U.S. market – with the potential to change the lives of many patients. Idorsia was listed on the SIX Swiss Exchange (ticker symbol: IDIA) in June 2017.

For further information, please contact

U.S. Media:

Christopher Clark
Head, U.S. Communications
Idorsia Pharmaceuticals U.S. Inc., One Radnor Corporate Center, Suite 101, 100 Matsonford Rd, Radnor, PA 19087
215-421-4887
Email Contact
www.idorsia.com

Global Investors:

Andrew C. Weiss
Senior Vice President, Head of Investor Relations & Corporate Communications
Idorsia Pharmaceuticals Ltd, Hegenheimermattweg 91, CH-4123 Allschwil
+41 58 844 10 10
Email Contact
www.idorsia.com

The above information contains certain "forward-looking statements", relating to the company's business, which can be identified by the use of forward-looking terminology such as "estimates", "believes", "expects", "may", "are expected to", "will", "will continue", "should", "would be", "seeks", "pending" or "anticipates" or similar expressions, or by discussions of strategy, plans or intentions. Such statements include descriptions of the company's investment and research and development programs and anticipated expenditures in connection therewith, descriptions of new products expected to be introduced by the company and anticipated customer demand for such products and products in the company's existing portfolio. Such statements reflect the current views of the company with respect to future events and are subject to certain risks, uncertainties and assumptions. Many factors could cause the actual results, performance or achievements of the company to be materially different from any future results, performances or achievements that may be expressed or implied by such forward-looking statements. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described herein as anticipated, believed, estimated or expected.

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SOURCE Idorsia Pharmaceuticals U.S.